Molecular modeling evaluation of the binding effect of five protease inhibitors to COVID-19 main protease

Coronavirus disease 2019 (COVID-19) has caused more than 840,000 deaths as of 31 August 2020 in the whole world. The COVID-19 main protease (M(pro)) has been validated as an attractive target for drug design. In this work, the binding mechanisms of five protease inhibitors (e.g., danoprevir, darunav...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Jian, Zhai, You, Liang, Lijun, Zhu, Danyan, Zhao, Qingwei, Qiu, Yunqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834164/
https://www.ncbi.nlm.nih.gov/pubmed/33519023
http://dx.doi.org/10.1016/j.chemphys.2020.111080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834164/
https://www.ncbi.nlm.nih.gov/pubmed/33519023
http://dx.doi.org/10.1016/j.chemphys.2020.111080

Ejemplares similares