RNA sequence and ligand binding alter conformational profile of SARS-CoV-2 stem loop II motif

Antiviral drug discovery continues to be an essential complement to vaccine development for overcoming the global pandemic caused by SARS-CoV-2. The genomic RNA of SARS-CoV-2 contains structural elements important for viral replication and/or pathogenesis making them potential therapeutic targets. H...

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Detalles Bibliográficos
Autores principales: Aldhumani, Ali H., Hossain, Md Ismail, Fairchild, Emily A., Boesger, Hannah, Marino, Emily C., Myers, Mason, Hines, Jennifer V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834705/
https://www.ncbi.nlm.nih.gov/pubmed/33545635
http://dx.doi.org/10.1016/j.bbrc.2021.01.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834705/
https://www.ncbi.nlm.nih.gov/pubmed/33545635
http://dx.doi.org/10.1016/j.bbrc.2021.01.013

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