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RNA sequence and ligand binding alter conformational profile of SARS-CoV-2 stem loop II motif
Antiviral drug discovery continues to be an essential complement to vaccine development for overcoming the global pandemic caused by SARS-CoV-2. The genomic RNA of SARS-CoV-2 contains structural elements important for viral replication and/or pathogenesis making them potential therapeutic targets. H...
Autores principales: | Aldhumani, Ali H., Hossain, Md Ismail, Fairchild, Emily A., Boesger, Hannah, Marino, Emily C., Myers, Mason, Hines, Jennifer V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834705/ https://www.ncbi.nlm.nih.gov/pubmed/33545635 http://dx.doi.org/10.1016/j.bbrc.2021.01.013 |
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