Molecular docking simulation reveals ACE2 polymorphisms that may increase the affinity of ACE2 with the SARS-CoV-2 Spike protein

There is increasing evidence that ACE2 gene polymorphism can modulate the interaction between ACE2 and the SARS-CoV-2 spike protein affecting the viral entry into the host cell, and/or contribute to lung and systemic damage in COVID-19. Here we used in silico molecular docking to predict the effects...

Descripción completa

Detalles Bibliográficos
Autores principales: Calcagnile, Matteo, Forgez, Patricia, Iannelli, Antonio, Bucci, Cecilia, Alifano, Marco, Alifano, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. and Société Française de Biochimie et Biologie Moléculaire (SFBBM). 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834737/
https://www.ncbi.nlm.nih.gov/pubmed/33181224
http://dx.doi.org/10.1016/j.biochi.2020.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834737/
https://www.ncbi.nlm.nih.gov/pubmed/33181224
http://dx.doi.org/10.1016/j.biochi.2020.11.004

Ejemplares similares