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Nsd2 Represses Endogenous Retrovirus MERVL in Embryonic Stem Cells

The facilitates chromatin transcription (FACT) complex is a histone H2A/H2B chaperone, which represses endogenous retroviruses (ERVs) and transcription of ERV-chimeric transcripts. It binds to both transcription start site and gene body region. Here, we investigated the downstream targets of FACT co...

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Detalles Bibliográficos
Autores principales: Gao, Tingting, Chen, Fuquan, Zhang, Wenying, Zhao, Xuan, Hu, Xiao, Lu, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834818/
https://www.ncbi.nlm.nih.gov/pubmed/33531910
http://dx.doi.org/10.1155/2021/6663960