P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk

Osteoarthritis (OA) is an urgent public health problem; however, the underlying causal mechanisms remain unclear, especially in terms of inflammatory mediators in cartilage degradation and chondrocyte imbalance. P2X7 receptor (P2X7R) is a critical inflammation switch, but few studies have examined i...

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Detalles Bibliográficos
Autores principales: Li, Zihao, Huang, Ziyu, Zhang, He, Lu, Jinghan, Tian, Yicheng, Wei, Yingliang, Yang, Yue, Bai, Lunhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834826/
https://www.ncbi.nlm.nih.gov/pubmed/33532039
http://dx.doi.org/10.1155/2021/8868361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834826/
https://www.ncbi.nlm.nih.gov/pubmed/33532039
http://dx.doi.org/10.1155/2021/8868361

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