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Obesity as a Possible Risk Factor for Progression from Monoclonal Gammopathy of Undetermined Significance Progression into Multiple Myeloma: Could Myeloma Be Prevented with Metformin Treatment?

Obesity is increasingly associated with the transformation of monoclonal gammopathy of undetermined significance (MGUS) into multiple myeloma (MM). Obesity, MGUS, and MM share common etiopathogenesis mechanisms including altered insulin axis and the action of inflammatory cytokines. Consistent with...

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Detalles Bibliográficos
Autores principales: da Cunha Júnior, Ademar Dantas, Zanette, Dalila Luciola, Pericole, Fernando Vieira, Olalla Saad, Sara Teresinha, Barreto Campello Carvalheira, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834834/
https://www.ncbi.nlm.nih.gov/pubmed/33531904
http://dx.doi.org/10.1155/2021/6615684