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Apremilast prevents IL-17-induced cellular senescence in ATDC5 chondrocytes mediated by SIRT1
Osteoarthritis is the most prevalent joint degenerative disease and has been considered a major cause of severe joint pain and physical disability in the elderly. The chondrocyte is the only cell type found in articular cartilage and chondrocyte senescence plays a pivotal role in the pathogenesis of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834959/ https://www.ncbi.nlm.nih.gov/pubmed/33448323 http://dx.doi.org/10.3892/ijmm.2021.4845 |