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Apremilast prevents IL-17-induced cellular senescence in ATDC5 chondrocytes mediated by SIRT1

Osteoarthritis is the most prevalent joint degenerative disease and has been considered a major cause of severe joint pain and physical disability in the elderly. The chondrocyte is the only cell type found in articular cartilage and chondrocyte senescence plays a pivotal role in the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Wang, Benlong, Sun, Wei, Bi, Kunwei, Li, Yong, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834959/
https://www.ncbi.nlm.nih.gov/pubmed/33448323
http://dx.doi.org/10.3892/ijmm.2021.4845

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