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Astragaloside IV alleviates silica-induced pulmonary fibrosis via inactivation of the TGF-β1/Smad2/3 signaling pathway

The aim of the present study was to investigate the anti-fibrotic effects of astragaloside IV (ASV) in silicosis rats, and to further explore the potential underlying molecular mechanisms. A silica-induced rat model of pulmonary fibrosis was successfully constructed. Hematoxylin and eosin and Masson...

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Detalles Bibliográficos
Autores principales: Li, Nannan, Wu, Ke, Feng, Feifei, Wang, Lin, Zhou, Xiang, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834968/
https://www.ncbi.nlm.nih.gov/pubmed/33448318
http://dx.doi.org/10.3892/ijmm.2021.4849