CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson’s disease

Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson’s disease (PD). Carboxyl terminus of Hsp70-interacting protein (CHIP) is a key regulator of mitochondrial dynamics, and mutations in CHIP or deficits in its expression have been associated with various neurological diseas...

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Detalles Bibliográficos
Autores principales: Hu, Zhengwei, Mao, Chengyuan, Wang, Hui, Zhang, Zhongxian, Zhang, Shuo, Luo, Haiyang, Tang, Mibo, Yang, Jing, Yuan, Yanpeng, Wang, Yanlin, Liu, Yutao, Fan, Liyuan, Zhang, Qimeng, Yao, Dabao, Liu, Fen, Schisler, Jonathan C., Shi, Changhe, Xu, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834979/
https://www.ncbi.nlm.nih.gov/pubmed/33472166
http://dx.doi.org/10.18632/aging.202389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834979/
https://www.ncbi.nlm.nih.gov/pubmed/33472166
http://dx.doi.org/10.18632/aging.202389

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