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CHIP protects against MPP(+)/MPTP-induced damage by regulating Drp1 in two models of Parkinson’s disease
Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson’s disease (PD). Carboxyl terminus of Hsp70-interacting protein (CHIP) is a key regulator of mitochondrial dynamics, and mutations in CHIP or deficits in its expression have been associated with various neurological diseas...
Autores principales: | Hu, Zhengwei, Mao, Chengyuan, Wang, Hui, Zhang, Zhongxian, Zhang, Shuo, Luo, Haiyang, Tang, Mibo, Yang, Jing, Yuan, Yanpeng, Wang, Yanlin, Liu, Yutao, Fan, Liyuan, Zhang, Qimeng, Yao, Dabao, Liu, Fen, Schisler, Jonathan C., Shi, Changhe, Xu, Yuming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834979/ https://www.ncbi.nlm.nih.gov/pubmed/33472166 http://dx.doi.org/10.18632/aging.202389 |
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