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SNRPB-mediated RNA splicing drives tumor cell proliferation and stemness in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the leading malignant diseases worldwide, but therapeutic targets for HCC are lacking. Here, we characterized a significant upregulation of Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB) in HCC via qRT-PCR, western blotting, tissue microarray a...

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Detalles Bibliográficos
Autores principales: Zhan, Yu-Ting, Li, Lei, Zeng, Ting-Ting, Zhou, Ning-Ning, Guan, Xin-Yuan, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834993/
https://www.ncbi.nlm.nih.gov/pubmed/33289700
http://dx.doi.org/10.18632/aging.202164