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In situ self-assembly of Au-antimiR-155 nanocomplexes mediates TLR3-dependent apoptosis in hepatocellular carcinoma cells

MicroRNA 155 (miRNA-155) is frequently dysregulated in hepatocellular carcinoma (HCC) and other cancer types. Toll-like receptor 3 (TLR3), a putative miR-155 target, plays a key role in liver pathophysiology, and its downregulation in HCC cells is associated with apoptosis evasion and poor outcomes....

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Detalles Bibliográficos
Autores principales: Yin, Liang, Cai, Weijuan, Liang, Yongqian, Yao, Jie, Wang, Xuemei, Shen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834998/
https://www.ncbi.nlm.nih.gov/pubmed/33173017
http://dx.doi.org/10.18632/aging.103799