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Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice

Parkinson’s disease (PD) is a neurodegenerative disease caused by the loss of dopaminergic neurons. It is characterized by static tremors, stiffness, slow movements, and gait disturbances, but it is also accompanied by anxiety and depression. Our previous study showed that atorvastatin could reduce...

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Detalles Bibliográficos
Autores principales: Yan, Junqiang, Huang, Jiarui, Liu, Anran, Wu, Jiannan, Fan, Hua, Shen, Mengmeng, Lai, Xiaoyi, Ma, Hongxia, Sun, Wenjie, Yang, Jianxue, Xu, Yunqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835000/
https://www.ncbi.nlm.nih.gov/pubmed/33289703
http://dx.doi.org/10.18632/aging.202189