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Atorvastatin improves motor function, anxiety and depression by NOX2-mediated autophagy and oxidative stress in MPTP-lesioned mice
Parkinson’s disease (PD) is a neurodegenerative disease caused by the loss of dopaminergic neurons. It is characterized by static tremors, stiffness, slow movements, and gait disturbances, but it is also accompanied by anxiety and depression. Our previous study showed that atorvastatin could reduce...
Autores principales: | Yan, Junqiang, Huang, Jiarui, Liu, Anran, Wu, Jiannan, Fan, Hua, Shen, Mengmeng, Lai, Xiaoyi, Ma, Hongxia, Sun, Wenjie, Yang, Jianxue, Xu, Yunqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835000/ https://www.ncbi.nlm.nih.gov/pubmed/33289703 http://dx.doi.org/10.18632/aging.202189 |
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