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MITF functions as a tumor suppressor in non-small cell lung cancer beyond the canonically oncogenic role

Microphthalamia-associated transcription factor (MITF) is a critical mediator in melanocyte differentiation and exerts oncogenic functions in melanoma progression. However, the role of MITF in non-small cell lung cancer (NSCLC) is still unknown. We found that MITF is dominantly expressed in the low-...

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Detalles Bibliográficos
Autores principales: Hsiao, Yi-Jing, Chang, Wen-Hsin, Chen, Hsuan-Yu, Hsu, Yin-Chen, Chiu, Su-Chin, Chiang, Ching-Cheng, Chang, Gee-Chen, Chen, Yi-Ju, Wang, Chia-Yu, Chen, Yan-Ming, Lin, Chien-Yu, Chen, Yu-Ju, Yang, Pan-Chyr, Chen, Jeremy J.W., Yu, Sung-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835003/
https://www.ncbi.nlm.nih.gov/pubmed/33293474
http://dx.doi.org/10.18632/aging.202171