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Fbxo7 and Pink1 play a reciprocal role in regulating their protein levels

Pink1, Parkin and Fbxo7, three autosomal recessive familial genes of Parkinson’s disease (PD), have been implicated in mitophagy pathways for quality control and clearance of damaged mitochondria, but the interplay of these three genes still remains unclear. Here we present that Fbxo7 and Pink1 play...

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Detalles Bibliográficos
Autores principales: Huang, Tianwen, Fang, Lijun, He, Raoli, Weng, Huidan, Chen, Xiaochun, Ye, Qinyong, Qu, Dianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835017/
https://www.ncbi.nlm.nih.gov/pubmed/33291077
http://dx.doi.org/10.18632/aging.202236