Identification of a novel and potent small molecule inhibitor of SRPK1: mechanism of dual inhibition of SRPK1 for the inhibition of cancer progression

Protein kinases are the family of attractive enzyme targets for drug design with relevance to cancer biology. Serine arginine protein kinase 1 (SRPK1) is responsible for the phosphorylation of serine/arginine (SR)-rich proteins. Alternative Splicing Factor/Splicing Factor 2 (ASF/SF2) involved in mRN...

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Detalles Bibliográficos
Autores principales: Chandra, Anshuman, Ananda, Hanumappa, Singh, Nagendra, Qamar, Imteyaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835025/
https://www.ncbi.nlm.nih.gov/pubmed/33291073
http://dx.doi.org/10.18632/aging.202301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835025/
https://www.ncbi.nlm.nih.gov/pubmed/33291073
http://dx.doi.org/10.18632/aging.202301

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