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Tandem mass tag-based proteomic analysis reveals cathepsin-mediated anti-autophagic and pro-apoptotic effects under proliferative diabetic retinopathy

Proliferative diabetic retinopathy (PDR) is a severe complication of diabetes and can cause blindness. However, the available therapeutic modalities to PDR have unsatisfactory efficacies and incur adverse effects, which is due to the paucity in the understanding of pathogenic mechanisms responsible...

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Detalles Bibliográficos
Autores principales: Niu, Rui, Wang, Jindan, Geng, Chao, Li, Yahong, Dong, Lijie, Liu, Lin, Chang, Yuwen, Shen, Jianqun, Nie, Zetong, Zhang, Yan, Hu, Bojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835038/
https://www.ncbi.nlm.nih.gov/pubmed/33293479
http://dx.doi.org/10.18632/aging.202217