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Tandem mass tag-based proteomic analysis reveals cathepsin-mediated anti-autophagic and pro-apoptotic effects under proliferative diabetic retinopathy
Proliferative diabetic retinopathy (PDR) is a severe complication of diabetes and can cause blindness. However, the available therapeutic modalities to PDR have unsatisfactory efficacies and incur adverse effects, which is due to the paucity in the understanding of pathogenic mechanisms responsible...
Autores principales: | Niu, Rui, Wang, Jindan, Geng, Chao, Li, Yahong, Dong, Lijie, Liu, Lin, Chang, Yuwen, Shen, Jianqun, Nie, Zetong, Zhang, Yan, Hu, Bojie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835038/ https://www.ncbi.nlm.nih.gov/pubmed/33293479 http://dx.doi.org/10.18632/aging.202217 |
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