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Mechanical allodynia triggered by cold exposure in mice with the Scn11a p.R222S mutation: a novel model of drug therapy for neuropathic pain related to Na(V)1.9

Mutations within the SCN11A gene which encodes the voltage-gated sodium channel Na(V)1.9 mainly expressed in small fiber sensory neurons have been associated with neuropathic disorders; however, suitable medications have not been fully investigated. To develop drug therapies against Na(V)1.9-related...

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Detalles Bibliográficos
Autores principales: Matsubara, Yosuke, Okuda, Hiroko, Harada, Kouji H., Youssefian, Shohab, Koizumi, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835175/
https://www.ncbi.nlm.nih.gov/pubmed/32970203
http://dx.doi.org/10.1007/s00210-020-01978-z