Impact of phosphodiesterases PDE3 and PDE4 on 5-hydroxytryptamine receptor4-mediated increase of cAMP in human atrial fibrillation

Atrial fibrillation (AF)–associated remodeling includes contractile dysfunction whose reasons are only partially resolved. Serotonin (5-HT) increases contractile force and causes arrhythmias in atrial trabeculae from patients in sinus rhythm (SR). In persistent atrial fibrillation (peAF), the force...

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Detalles Bibliográficos
Autores principales: Dolce, Bernardo, Christ, Torsten, Grammatika Pavlidou, Nefeli, Yildirim, Yalin, Reichenspurner, Hermann, Eschenhagen, Thomas, Nikolaev, Viacheslav O., Kaumann, Alberto J, Molina, Cristina E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835186/
https://www.ncbi.nlm.nih.gov/pubmed/32949251
http://dx.doi.org/10.1007/s00210-020-01968-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835186/
https://www.ncbi.nlm.nih.gov/pubmed/32949251
http://dx.doi.org/10.1007/s00210-020-01968-1

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