Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock

Singular blockade of C5a in experimental models of sepsis is known to confer protection by rescuing lethality and decreasing pro-inflammatory responses. However, the role of inhibiting C5a has not been evaluated in the context of sterile systemic inflammatory responses, like polytrauma and hemorrhag...

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Detalles Bibliográficos
Autores principales: Chakraborty, Shinjini, Winkelmann, Veronika Eva, Braumüller, Sonja, Palmer, Annette, Schultze, Anke, Klohs, Bettina, Ignatius, Anita, Vater, Axel, Fauler, Michael, Frick, Manfred, Huber-Lang, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835219/
https://www.ncbi.nlm.nih.gov/pubmed/33495506
http://dx.doi.org/10.1038/s41598-020-79607-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835219/
https://www.ncbi.nlm.nih.gov/pubmed/33495506
http://dx.doi.org/10.1038/s41598-020-79607-1

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