Cargando…
Role of the C5a-C5a receptor axis in the inflammatory responses of the lungs after experimental polytrauma and hemorrhagic shock
Singular blockade of C5a in experimental models of sepsis is known to confer protection by rescuing lethality and decreasing pro-inflammatory responses. However, the role of inhibiting C5a has not been evaluated in the context of sterile systemic inflammatory responses, like polytrauma and hemorrhag...
Autores principales: | Chakraborty, Shinjini, Winkelmann, Veronika Eva, Braumüller, Sonja, Palmer, Annette, Schultze, Anke, Klohs, Bettina, Ignatius, Anita, Vater, Axel, Fauler, Michael, Frick, Manfred, Huber-Lang, Markus |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835219/ https://www.ncbi.nlm.nih.gov/pubmed/33495506 http://dx.doi.org/10.1038/s41598-020-79607-1 |
Ejemplares similares
-
Complement Factor C5a Inhibits Apoptosis of Neutrophils—A Mechanism in Polytrauma?
por: Ehrnthaller, Christian, et al.
Publicado: (2021) -
Early structural changes of the heart after experimental polytrauma and hemorrhagic shock
por: Braun, Christian K., et al.
Publicado: (2017) -
A New Experimental Polytrauma Model in Rats: Molecular Characterization of the Early Inflammatory Response
por: Weckbach, Sebastian, et al.
Publicado: (2012) -
Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury
por: Debler, Lisa, et al.
Publicado: (2021) -
Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma
por: Lupu, Ludmila, et al.
Publicado: (2022)