16S rRNA Gene Copy Number Normalization Does Not Provide More Reliable Conclusions in Metataxonomic Surveys

Sequencing 16S rRNA gene amplicons is the gold standard to uncover the composition of prokaryotic communities. The presence of multiple copies of this gene makes the community abundance data distorted and gene copy normalization (GCN) necessary for correction. Even though GCN of 16S data provided a...

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Detalles Bibliográficos
Autores principales: Starke, Robert, Pylro, Victor Satler, Morais, Daniel Kumazawa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835310/
https://www.ncbi.nlm.nih.gov/pubmed/32862246
http://dx.doi.org/10.1007/s00248-020-01586-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835310/
https://www.ncbi.nlm.nih.gov/pubmed/32862246
http://dx.doi.org/10.1007/s00248-020-01586-7

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