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Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions

Uncharacterized and unannotated open-reading frames, which we refer to as novel open reading frames (nORFs), may sometimes encode peptides that remain unexplored for novel therapeutic opportunities. To our knowledge, no systematic identification and characterization of transcripts encoding nORFs or...

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Detalles Bibliográficos
Autores principales: Erady, Chaitanya, Boxall, Adam, Puntambekar, Shraddha, Suhas Jagannathan, N., Chauhan, Ruchi, Chong, David, Meena, Narendra, Kulkarni, Apurv, Kasabe, Bhagyashri, Prathivadi Bhayankaram, Kethaki, Umrania, Yagnesh, Andreani, Adam, Nel, Jean, Wayland, Matthew T., Pina, Cristina, Lilley, Kathryn S., Prabakaran, Sudhakaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835362/
https://www.ncbi.nlm.nih.gov/pubmed/33495453
http://dx.doi.org/10.1038/s41525-020-00167-4