Mechanism of membrane-curvature generation by ER-tubule shaping proteins

The endoplasmic reticulum (ER) network consists of tubules with high membrane curvature in cross-section, generated by the reticulons and REEPs. These proteins have two pairs of trans-membrane (TM) segments, followed by an amphipathic helix (APH), but how they induce curvature is poorly understood....

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Detalles Bibliográficos
Autores principales: Wang, Ning, Clark, Lindsay D., Gao, Yuan, Kozlov, Michael M., Shemesh, Tom, Rapoport, Tom A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835363/
https://www.ncbi.nlm.nih.gov/pubmed/33495454
http://dx.doi.org/10.1038/s41467-020-20625-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835363/
https://www.ncbi.nlm.nih.gov/pubmed/33495454
http://dx.doi.org/10.1038/s41467-020-20625-y

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