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Mechanism of membrane-curvature generation by ER-tubule shaping proteins
The endoplasmic reticulum (ER) network consists of tubules with high membrane curvature in cross-section, generated by the reticulons and REEPs. These proteins have two pairs of trans-membrane (TM) segments, followed by an amphipathic helix (APH), but how they induce curvature is poorly understood....
Autores principales: | Wang, Ning, Clark, Lindsay D., Gao, Yuan, Kozlov, Michael M., Shemesh, Tom, Rapoport, Tom A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835363/ https://www.ncbi.nlm.nih.gov/pubmed/33495454 http://dx.doi.org/10.1038/s41467-020-20625-y |
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