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Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy

Cumulative evidence suggests added benefit for neoadjuvant chemotherapy (NAC) in a subset of triple-negative breast cancer (TNBC) patients. Herein we identified the long noncoding RNA (lncRNA) transcriptional landscape associated with TNBC resistance to NAC, employing 1758 single cells from three ex...

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Detalles Bibliográficos
Autores principales: Shaath, Hibah, Vishnubalaji, Radhakrishnan, Elango, Ramesh, Khattak, Shahryar, Alajez, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835365/
https://www.ncbi.nlm.nih.gov/pubmed/33495450
http://dx.doi.org/10.1038/s41420-020-00383-y