Cargando…
Single-cell long noncoding RNA (lncRNA) transcriptome implicates MALAT1 in triple-negative breast cancer (TNBC) resistance to neoadjuvant chemotherapy
Cumulative evidence suggests added benefit for neoadjuvant chemotherapy (NAC) in a subset of triple-negative breast cancer (TNBC) patients. Herein we identified the long noncoding RNA (lncRNA) transcriptional landscape associated with TNBC resistance to NAC, employing 1758 single cells from three ex...
Autores principales: | Shaath, Hibah, Vishnubalaji, Radhakrishnan, Elango, Ramesh, Khattak, Shahryar, Alajez, Nehad M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835365/ https://www.ncbi.nlm.nih.gov/pubmed/33495450 http://dx.doi.org/10.1038/s41420-020-00383-y |
Ejemplares similares
-
Protein Coding and Long Noncoding RNA (lncRNA) Transcriptional Landscape in SARS-CoV-2 Infected Bronchial Epithelial Cells Highlight a Role for Interferon and Inflammatory Response
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2020) -
Molecular subtyping and functional validation of TTK, TPX2, UBE2C, and LRP8 in sensitivity of TNBC to paclitaxel
por: Elango, Ramesh, et al.
Publicado: (2021) -
Molecular Classification of Breast Cancer Utilizing Long Non-Coding RNA (lncRNA) Transcriptomes Identifies Novel Diagnostic lncRNA Panel for Triple-Negative Breast Cancer
por: Shaath, Hibah, et al.
Publicado: (2021) -
Transcriptional alterations of protein coding and noncoding RNAs in triple negative breast cancer in response to DNA methyltransferases inhibition
por: Elango, Ramesh, et al.
Publicado: (2021) -
LncRNA-Based Classification of Triple Negative Breast Cancer Revealed Inherent Tumor Heterogeneity and Vulnerabilities
por: Vishnubalaji, Radhakrishnan, et al.
Publicado: (2022)