Intracellular alpha-fetoprotein interferes with all-trans retinoic acid induced ATG7 expression and autophagy in hepatocellular carcinoma cells

Retinoic acid and retinoid acid receptor (RA-RAR) signaling exhibits suppressive functions in the progression of hepatocellular carcinoma (HCC) through multiple mechanisms. However, whether RA-RAR signaling induces autophagy that contributes its anti-tumor activity in HCC remains elusive. In the cur...

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Detalles Bibliográficos
Autores principales: Wang, Shanshan, Feng, Rilu, Shi, Ying, Chen, Dexi, Weng, Honglei, Ding, Huiguo, Zhang, Chenguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835378/
https://www.ncbi.nlm.nih.gov/pubmed/33495541
http://dx.doi.org/10.1038/s41598-021-81678-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835378/
https://www.ncbi.nlm.nih.gov/pubmed/33495541
http://dx.doi.org/10.1038/s41598-021-81678-7

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