Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes

Bloom Syndrome (BS; OMIM #210900; ORPHA #125) is a rare genetic disorder that is associated with growth deficits, compromised immune system, insulin resistance, genome instability and extraordinary predisposition to cancer. Most efforts thus far have focused on understanding the role of the Bloom sy...

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Detalles Bibliográficos
Autores principales: Subramanian, Veena, Rodemoyer, Brian, Shastri, Vivek, Rasmussen, Lene J., Desler, Claus, Schmidt, Kristina H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835382/
https://www.ncbi.nlm.nih.gov/pubmed/33495511
http://dx.doi.org/10.1038/s41598-021-81075-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835382/
https://www.ncbi.nlm.nih.gov/pubmed/33495511
http://dx.doi.org/10.1038/s41598-021-81075-0

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