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A binding protein regulates myosin-7a dimerization and actin bundle assembly

Myosin-7a, despite being monomeric in isolation, plays roles in organizing actin-based cell protrusions such as filopodia, microvilli and stereocilia, as well as transporting cargoes within them. Here, we identify a binding protein for Drosophila myosin-7a termed M7BP, and describe how M7BP assemble...

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Detalles Bibliográficos
Autores principales: Liu, Rong, Billington, Neil, Yang, Yi, Bond, Charles, Hong, Amy, Siththanandan, Verl, Takagi, Yasuharu, Sellers, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835385/
https://www.ncbi.nlm.nih.gov/pubmed/33495456
http://dx.doi.org/10.1038/s41467-020-20864-z