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Renin profiling predicts neurohormonal response to sacubitril/valsartan

AIMS: Clinical trials and observational cohorts show that beneficial effects of sacubitril/valsartan are less strong in an appreciable proportion of patients with heart failure with reduced ejection fraction (HFrEF). Lower blood pressure and impaired renal function predict suboptimal sacubitril/vals...

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Detalles Bibliográficos
Autores principales: Vergaro, Giuseppe, Sciarrone, Paolo, Prontera, Concetta, Masotti, Silvia, Musetti, Veronica, Valleggi, Alessandro, Giannoni, Alberto, Senni, Michele, Emdin, Michele, Passino, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835599/
https://www.ncbi.nlm.nih.gov/pubmed/33216460
http://dx.doi.org/10.1002/ehf2.13085