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The evolution of alternative splicing in glioblastoma under therapy

BACKGROUND: Alternative splicing is a rich source of tumor-specific neoantigen targets for immunotherapy. This holds promise for glioblastomas (GBMs), the most common primary tumors of the adult brain, which are resistant to standard-of-care therapy. Although most clinical trials enroll patients at...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Shamardani, Karin, Babikir, Husam, Catalan, Francisca, Nejo, Takahide, Chang, Susan, Phillips, Joanna J., Okada, Hideho, Diaz, Aaron A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835670/
https://www.ncbi.nlm.nih.gov/pubmed/33499924
http://dx.doi.org/10.1186/s13059-021-02259-5