Genetic and Pharmacological Manipulations of Glyoxalase 1 Mediate Ethanol Withdrawal Seizure Susceptibility in Mice

Central nervous system (CNS) hyperexcitability is a clinically significant feature of acute ethanol withdrawal. There is evidence for a genetic contribution to withdrawal severity, but specific genetic risk factors have not been identified. The gene glyoxalase 1 (Glo1) has been previously implicated...

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Detalles Bibliográficos
Autores principales: Barkley-Levenson, Amanda M., Lee, Amy, Palmer, Abraham A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835754/
https://www.ncbi.nlm.nih.gov/pubmed/33478138
http://dx.doi.org/10.3390/brainsci11010127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835754/
https://www.ncbi.nlm.nih.gov/pubmed/33478138
http://dx.doi.org/10.3390/brainsci11010127

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