Ex Vivo Mitochondrial Respiration Parallels Biochemical Response to Ibrutinib in CLL Cells

SIMPLE SUMMARY: Chronic lymphocytic leukemia (CLL) is a cancer that is characterized by dysfunctional mitochondria. This results in a deranged mitochondrial metabolism. Many drugs are tested using simple live or dead cell assays and as such the impact on the altered mitochondrial function is not eva...

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Detalles Bibliográficos
Autores principales: Chowdhury, Subir Roy, Peltier, Cheryl, Hou, Sen, Singh, Amandeep, Johnston, James B., Gibson, Spencer B., Marshall, Aaron J., Banerji, Versha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835851/
https://www.ncbi.nlm.nih.gov/pubmed/33477957
http://dx.doi.org/10.3390/cancers13020354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835851/
https://www.ncbi.nlm.nih.gov/pubmed/33477957
http://dx.doi.org/10.3390/cancers13020354

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