ABT-751 Induces Multiple Anticancer Effects in Urinary Bladder Urothelial Carcinoma-Derived Cells: Highlighting the Induction of Cytostasis through the Inhibition of SKP2 at Both Transcriptional and Post-Translational Levels

The objective was to investigate the anti-cancer effects and underlying molecular mechanisms of cytostasis which were activated by an anti-microtubule drug, ABT-751, in two urinary bladder urothelial carcinoma (UBUC)-derived cell lines, BFTC905 and J82, with distinct genetic backgrounds. A series of...

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Detalles Bibliográficos
Autores principales: Dehghanian, Seyedeh Zahra, Pan, Cheng-Tang, Lee, Jasmine Marianne, Shiue, Yow-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835924/
https://www.ncbi.nlm.nih.gov/pubmed/33478005
http://dx.doi.org/10.3390/ijms22020945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835924/
https://www.ncbi.nlm.nih.gov/pubmed/33478005
http://dx.doi.org/10.3390/ijms22020945

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