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Correlative Microscopy to Localize and Characterize Iron Deposition in Alzheimer’s Disease

BACKGROUND: Recent evidence suggests that the accumulation of iron, specifically ferrous Fe(2+), may play a role in the development and progression of neurodegeneration in Alzheimer’s disease (AD) through the production of oxidative stress. OBJECTIVE: To localize and characterize iron deposition and...

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Detalles Bibliográficos
Autores principales: Madsen, Steven J., DiGiacomo, Phillip S., Zeng, Yitian, Goubran, Maged, Chen, Yuanxin, Rutt, Brian K., Born, Donald, Vogel, Hannes, Sinclair, Robert, Zeineh, Michael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835989/
https://www.ncbi.nlm.nih.gov/pubmed/33532700
http://dx.doi.org/10.3233/ADR-200234