Cargando…

Physical Interaction between HPV16E7 and the Actin-Binding Protein Gelsolin Regulates Epithelial-Mesenchymal Transition via HIPPO-YAP Axis

SIMPLE SUMMARY: Human papilloma viruses cause benign or malignant hyper-proliferative lesions in cervical, anogenital and oropharyngeal tissues. Our previous studies revealed that HPV16 E7 alters actin cytoskeleton mainly by binding to and inhibiting Gelsolin. We suggest that the physical interactio...

Descripción completa

Detalles Bibliográficos
Autores principales: Matarrese, Paola, Vona, Rosa, Ascione, Barbara, Paggi, Marco G., Mileo, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836002/
https://www.ncbi.nlm.nih.gov/pubmed/33477952
http://dx.doi.org/10.3390/cancers13020353