Cargando…

Physical Interaction between HPV16E7 and the Actin-Binding Protein Gelsolin Regulates Epithelial-Mesenchymal Transition via HIPPO-YAP Axis

SIMPLE SUMMARY: Human papilloma viruses cause benign or malignant hyper-proliferative lesions in cervical, anogenital and oropharyngeal tissues. Our previous studies revealed that HPV16 E7 alters actin cytoskeleton mainly by binding to and inhibiting Gelsolin. We suggest that the physical interactio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matarrese, Paola, Vona, Rosa, Ascione, Barbara, Paggi, Marco G., Mileo, Anna Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836002/ https://www.ncbi.nlm.nih.gov/pubmed/33477952 http://dx.doi.org/10.3390/cancers13020353

Ejemplares similares

Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness
por: Matarrese, Paola, et al.
Publicado: (2016)

Tumor Microenvironmental Cytokines Drive NSCLC Cell Aggressiveness and Drug-Resistance via YAP-Mediated Autophagy
por: Matarrese, Paola, et al.
Publicado: (2023)

Gelsolin-like actin-capping protein has prognostic value and promotes tumorigenesis and epithelial-mesenchymal transition via the Hippo signaling pathway in human bladder cancer
por: Zhaojie, Lyu, et al.
Publicado: (2019)

WWC3 inhibits epithelial–mesenchymal transition of lung cancer by activating Hippo-YAP signaling
por: Han, Qiang, et al.
Publicado: (2018)

Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study
por: Matarrese, Paola, et al.
Publicado: (2010)

Kinetic analysis of F-actin depolymerization in the presence of platelet gelsolin and gelsolin-actin complexes
Publicado: (1985)

SOX9 promotes epithelial-mesenchymal transition via the Hippo-YAP signaling pathway in gastric carcinoma cells
por: Zhou, Hailang, et al.
Publicado: (2019)

Notch3 inhibits epithelial–mesenchymal transition by activating Kibra-mediated Hippo/YAP signaling in breast cancer epithelial cells
por: Zhang, X, et al.
Publicado: (2016)

Gelsolin-actin interaction and actin polymerization in human neutrophils
Publicado: (1990)

Upregulation of CD109 Promotes the Epithelial-to-Mesenchymal Transition and Stemness Properties of Lung Adenocarcinomas via Activation of the Hippo-YAP Signaling
por: Lee, Kang-Yun, et al.
Publicado: (2020)

GABAB receptor inhibits tumor progression and epithelial-mesenchymal transition via the regulation of Hippo/YAP1 pathway in colorectal cancer
por: Wang, Huihui, et al.
Publicado: (2021)

Involvement of gelsolin in TGF-beta 1 induced epithelial to mesenchymal transition in breast cancer cells
por: Chen, Zhi-Yuan, et al.
Publicado: (2015)

The actin filament-severing domain of plasma gelsolin
Publicado: (1986)

Gelsolin has three actin-binding sites
Publicado: (1988)

Microtubule-Based Mitochondrial Dynamics as a Valuable Therapeutic Target in Cancer
por: Vona, Rosa, et al.
Publicado: (2021)

Regulation of the Hippo/YAP axis by CXCR7 in the tumorigenesis of gastric cancer
por: Wang, Tianshi, et al.
Publicado: (2023)

YAP and the Hippo pathway in cholangiocarcinoma
por: Sugihara, Takaaki, et al.
Publicado: (2019)

Regorafenib inhibits epithelial-mesenchymal transition and suppresses cholangiocarcinoma metastasis via YAP1-AREG axis
por: Chang, Yu-Chan, et al.
Publicado: (2022)

Gelsolin Promotes Cancer Progression by Regulating Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma and Correlates with a Poor Prognosis
por: Zhang, Yixi, et al.
Publicado: (2020)

The Hippo/YAP pathway interacts with EGFR signaling and HPV oncoproteins to regulate cervical cancer progression
por: He, Chunbo, et al.
Publicado: (2015)

Gelsolin inhibits autophagy by regulating actin depolymerization in pancreatic ductal epithelial cells in acute pancreatitis
por: Yang, Huiying, et al.
Publicado: (2023)

Plasma Gelsolin Levels Decrease in Diabetic State and Increase upon Treatment with F-Actin Depolymerizing Versions of Gelsolin
por: Khatri, Neeraj, et al.
Publicado: (2014)

Hippo-YAP/TAZ signaling in angiogenesis
por: Park, Jeong Ae, et al.
Publicado: (2018)

The Hippo Pathway Effector YAP1 Regulates Intestinal Epithelial Cell Differentiation
por: Fallah, Sepideh, et al.
Publicado: (2020)

Pin1/YAP pathway mediates matrix stiffness‐induced epithelial–mesenchymal transition driving cervical cancer metastasis via a non‐Hippo mechanism
por: Yang, Long, et al.
Publicado: (2022)

Plasma gelsolin promotes re-epithelialization
por: Wittmann, J., et al.
Publicado: (2018)

Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms
por: Dobrokhotov, Oleg, et al.
Publicado: (2018)

Piezo 1 activation facilitates cholangiocarcinoma metastasis via Hippo/YAP signaling axis
por: Zhu, Biqiang, et al.
Publicado: (2021)

Are the conserved sequences in segment 1 of gelsolin important for binding actin?
Publicado: (1992)

Association of gelsolin with actin filaments and cell membranes of macrophages and platelets
Publicado: (1989)

Reversible binding of actin to gelsolin and profilin in human platelet extracts
Publicado: (1987)

Plasma Actin, Gelsolin and Orosomucoid Levels after Eccentric Exercise
por: Tékus, Éva, et al.
Publicado: (2017)

The Activities of the Gelsolin Homology Domains of Flightless-I in Actin Dynamics
por: Pintér, Réka, et al.
Publicado: (2020)

Hippo transducer TAZ promotes epithelial mesenchymal transition and supports pancreatic cancer progression
por: Xie, Dacheng, et al.
Publicado: (2015)

Piezo1 activation facilitates ovarian cancer metastasis via Hippo/YAP signaling axis
por: Xiong, Yanjie, et al.
Publicado: (2022)

RBCK1 is an endogenous inhibitor for triple negative breast cancer via hippo/YAP axis
por: Li, Zhongbo, et al.
Publicado: (2022)

The Multiple Interactions of RUNX with the Hippo–YAP Pathway
por: Chuang, Linda Shyue Huey, et al.
Publicado: (2021)

Hippo-Yap/Taz signalling in zebrafish regeneration
por: Riley, Susanna E., et al.
Publicado: (2022)

Plasma Gelsolin Depletion and Circulating Actin in Sepsis—A Pilot Study
por: Lee, Po-Shun, et al.
Publicado: (2008)

Myosin and gelsolin cooperate in actin filament severing and actomyosin motor activity
por: Vemula, Venukumar, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gdu25thadtkk5cbrf381tuis8c