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The Combined Effect of APOE and BDNF Val66Met Polymorphisms on Spatial Navigation in Older Adults

BACKGROUND: The apolipoprotein E (APOE) ɛ4 allele is associated with episodic memory and spatial navigation deficits. The brain-derived neurotrophic factor (BDNF) Met allele may further worsen memory impairment in APOE ɛ4 carriers but its role in APOE ɛ4-related spatial navigation deficits has not b...

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Detalles Bibliográficos
Autores principales: Laczó, Jan, Cechova, Katerina, Parizkova, Martina, Lerch, Ondrej, Andel, Ross, Matoska, Vaclav, Kaplan, Vojtech, Matuskova, Veronika, Nedelska, Zuzana, Vyhnalek, Martin, Hort, Jakub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836052/
https://www.ncbi.nlm.nih.gov/pubmed/33325388
http://dx.doi.org/10.3233/JAD-200615