F-domain valency determines outcome of signaling through the angiopoietin pathway

Angiopoietin 1 and 2 (Ang1 and Ang2) modulate angiogenesis and vascular homeostasis through engagement of their very similar F-domain modules with the Tie2 receptor tyrosine kinase on endothelial cells. Despite this similarity in the underlying receptor binding interaction, the two angiopoietins hav...

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Detalles Bibliográficos
Autores principales: Zhao, Yan Ting, Fallas, Jorge A., Saini, Shally, Ueda, George, Somasundaram, Logeshwaran, Zhou, Ziben, Xavier, Infencia, Ehnes, Devon, Xu, Chunfu, Carter, Lauren, Wrenn, Samuel, Mathieu, Julie, Sellers, Drew L., Baker, David, Ruohola-Baker, Hannele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836102/
https://www.ncbi.nlm.nih.gov/pubmed/33501432
http://dx.doi.org/10.1101/2020.09.19.304188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836102/
https://www.ncbi.nlm.nih.gov/pubmed/33501432
http://dx.doi.org/10.1101/2020.09.19.304188

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