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Co‐administration of 2’3’-cGAMP STING activator and CpG-C adjuvants with a mutated form of HPV 16 E7 protein leads to tumor growth inhibition in the mouse model

Persistent infection with high-risk genotypes of human papillomavirus (HPV) is the leading cause of cervical cancer. The HPV oncoprotein E7 is constitutively expressed in cervical cancer and considered as an essential target for tumor-specific immunity. The goal of this study was to develop a candid...

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Detalles Bibliográficos
Autores principales: Dorostkar, Fariba, Arashkia, Arash, Roohvand, Farzin, Shoja, Zabihollah, Navari, Mohsen, Mashhadi Abolghasem Shirazi, Maryam, Shahosseini, Zahra, Farahmand, Mohammad, Shams nosrati, Mohammad Sadegh, Jalilvand, Somayeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836183/
https://www.ncbi.nlm.nih.gov/pubmed/33499895
http://dx.doi.org/10.1186/s13027-021-00346-7