Donor-derived, cell-free DNA levels by next-generation targeted sequencing are elevated in allograft rejection after lung transplantation

Surveillance after lung transplantation is critical to the detection of acute cellular rejection (ACR) and prevention of chronic lung allograft dysfunction (CLAD). Therefore, we measured donor-derived cell-free DNA (dd-cfDNA) implementing a clinical-grade, next-generation targeted sequencing assay i...

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Detalles Bibliográficos
Autores principales: Khush, Kiran K., De Vlaminck, Iwijn, Luikart, Helen, Ross, David J., Nicolls, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836440/
https://www.ncbi.nlm.nih.gov/pubmed/33532456
http://dx.doi.org/10.1183/23120541.00462-2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836440/
https://www.ncbi.nlm.nih.gov/pubmed/33532456
http://dx.doi.org/10.1183/23120541.00462-2020

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