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Losartan reduces cigarette smoke-induced airway inflammation and mucus hypersecretion

The aim was to determine whether losartan reduces cigarette smoke (CS)-induced airway inflammation and mucus hypersecretion in an in vitro model and a small clinical trial. Primary human bronchial epithelial cells (HBECs) were differentiated at the air–liquid interface (ALI) and exposed to CS. Expre...

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Detalles Bibliográficos
Autores principales: Kim, Michael D., Baumlin, Nathalie, Dennis, John S., Yoshida, Makoto, Kis, Adrian, Aguiar, Carolina, Schmid, Andreas, Mendes, Eliana, Salathe, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836504/
https://www.ncbi.nlm.nih.gov/pubmed/33532463
http://dx.doi.org/10.1183/23120541.00394-2020