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Akt signaling is activated by TGFβ2 and impacts tenogenic induction of mesenchymal stem cells

BACKGROUND: Tissue engineered and regenerative approaches for treating tendon injuries are challenged by the limited information on the cellular signaling pathways driving tenogenic differentiation of stem cells. Members of the transforming growth factor (TGF) β family, particularly TGFβ2, play a ro...

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Detalles Bibliográficos
Autores principales: Theodossiou, Sophia K., Murray, Jett B., Hold, LeeAnn A., Courtright, Jeff M., Carper, Anne M., Schiele, Nathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836508/
https://www.ncbi.nlm.nih.gov/pubmed/33499914
http://dx.doi.org/10.1186/s13287-021-02167-2