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Akt signaling is activated by TGFβ2 and impacts tenogenic induction of mesenchymal stem cells
BACKGROUND: Tissue engineered and regenerative approaches for treating tendon injuries are challenged by the limited information on the cellular signaling pathways driving tenogenic differentiation of stem cells. Members of the transforming growth factor (TGF) β family, particularly TGFβ2, play a ro...
Autores principales: | Theodossiou, Sophia K., Murray, Jett B., Hold, LeeAnn A., Courtright, Jeff M., Carper, Anne M., Schiele, Nathan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836508/ https://www.ncbi.nlm.nih.gov/pubmed/33499914 http://dx.doi.org/10.1186/s13287-021-02167-2 |
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