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Furin cleavage sites naturally occur in coronaviruses

The spike protein is a focused target of COVID-19, a pandemic caused by SARS-CoV-2. A 12-nt insertion at S1/S2 in the spike coding sequence yields a furin cleavage site, which raised controversy views on origin of the virus. Here we analyzed the phylogenetic relationships of coronavirus spike protei...

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Detalles Bibliográficos
Autores principales: Wu, Yiran, Zhao, Suwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7836551/
https://www.ncbi.nlm.nih.gov/pubmed/33340798
http://dx.doi.org/10.1016/j.scr.2020.102115